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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22262 | Ansamitocin p-3 | Maytansinol isobutyrate,Antibiotic C 15003P3,NSC292222 | Microtubule Associated |
Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization. | |||
T1910 | Ansamitocin P 3' | Maytansinol butyrate,Ansamitocin P-3,Antibiotic C 15003P3' | Microtubule Associated |
Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity. | |||
T40838 | 20-O-Demethyl-AP3 | 20-O-Demethyl-AP3 | |
20-O-Demethyl-AP3 is a secondary metabolite derived from Ansamitocin P-3, and Ansamitocin P-3 is a macrocyclic antitumor antibiotic exerting its therapeutic effects by inhibiting microtubules. | |||
T40883 | N-Demethylansamitocin P-3 | ||
N-Demethylansamitocin P-3, a derivative of Ansamitocin, an antitumor ansamycin antibiotic, can be synthesized through the action of Streptomyces minutiscleroticus IFO 13361. |